A diet rich in magnesium, polyphenols, and vitamin B is linked to decreased odds of depression in older adults over time.
A nutrient pattern rich in magnesium, hydroxybenzaldehydes, stilbenes, dihydroflavonols, vitamin B, lignans, tyrosols, and proanthocyanidins is associated with 15% lower odds of depressive symptomatology in older adults , a 15-year study showed.
Researchers analysed data of 1063 participants from the French Three-City cohort study from 2001 to 2018. Nutrient intake was assessed using 24-hour dietary recall interviews. Principal component analysis was performed on 40 selected nutrients, including 21 polyphenols, three carotenoids, five fatty acids, nine vitamins, and two minerals.Among the four identified nutrient patterns, the one involving a high intake of magnesium, hydroxybenzaldehydes, stilbenes, dihydroflavonols, lignans, tyrosols, folates, vitamins B6, B3, B5, and B1, and proanthocyanidins was associated with a decreased risk for DS over time ."This longitudinal study within a substantial cohort of older adults identified a nutrient pattern characterised by high consumptions of magnesium, hydroxybenzaldehydes, stilbenes, dihydroflavonols, vitamin B6, lignans, tyrosols, folates, vitamins B3, B5, B1, and proanthocyanidins, associated with a decreased odds of DS over a 15-year period," the authors wrote.The availability of dietary assessments only at baseline implied consistent dietary behaviours over time, though life events may have influenced daily routines. Although selection bias was initially present, it diminished over time. Additionally, assessing circulating nutrient levels may have yielded more accurate measurements than dietary records.The Three-City project received support from various sources. The present study was supported in part by Activ'Inside. Some authors reported being employed by a nutrition company, whereas others reported receiving grants, consulting fees, lecture payments, or travel support from various organisations. Details are provided in the original article. This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication. Bardinet J, Pouchieu C, Chuy V, et al. Association between nutrient patterns and odds of depressive symptomatology: A population-based cohort of older adults followed during 15-y. Published online February 11, 2025. doi:10.1007/s00394-025-03597-xAll material on this website is protected by copyright, Copyright © 1994-2025 by WebMD LLC. This website also contains material copyrighted by 3rd parties.
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