Results show promising leads and a whole new way to fight COVID-19. coronavirus
In the last 4 weeks, we have tested 47 of these drugs and compounds in the lab against live coronavirus. I’m happy to report we’ve identified some strong treatment leads and identified two separate mechanisms for how these drugs affect SARS-CoV-2 infection. Our findings wereEvery place that a coronavirus protein interacts with a human protein is a potential druggable site.
After infecting these monkey cells with live virus, our partners in Paris and New York added the drugs we identified to half and kept the other half as controls. They then measured the amount of virus in the samples and the number of cells that were alive. If the samples with drugs had a lower virus count and more cells alive compared to the control, that would suggest the drugs disrupt viral replication. The teams were also looking to see how toxic the drugs were to the cells.
It is incredibly important to remember that these are preliminary findings and have not been tested in people. No one should go out and buy these drugs.
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