Just spit and wait: First saliva-based test for new coronavirus offers advantages

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Just spit and wait: First saliva-based test for new coronavirus offers advantages
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Just spit and wait: First saliva-based test for new coronavirus offers advantages COVID19

A new test for the coronavirus is so simple and straightforward, almost anyone could do it: Spit a glob of saliva into a cup, close the lid and hand it over.

Starting about 2 weeks ago, New Jersey has offered the saliva test at a walk-up site in New Brunswick; drive-thru sites in Somerset and Edison; the state’s Department of Corrections; 30 long-term care facilities; and even the American Dream mall. Adalja noted that LabCorp, one of the nation’s largest commercial laboratories, now offers an at-home test that people can use to swab their own nose. “If we can do nasal swabs unsupervised, there’s no reason why we can’t do these tests unsupervised as well,” he said.

After a disastrously slow start, the United States is starting to see an increase in testing types and capacity. The National Institutes of Health on Wednesday announced a new $1.5 billion “shark tank” style program aimed at encouraging swift innovation in coronavirus testing, with a goal of new tests by the end of summer. Also Wednesday, testing manufacturer Hologic said that it had a new test that could allow labs to begin running up to 1 million additional tests per week.

The Rutgers test was validated in people who were severely ill, but the saliva test often yielded a stronger signal than the swab, suggesting that it is more sensitive — yielding fewer false negatives — than the swab. It also generated no false positives in all of the samples tested.In separate research, a Yale University team reported that saliva may be able to detect the virus in people who are only mildly ill, while a nasopharyngeal swab cannot.

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