Researchers at Trinity College Dublin have made a groundbreaking discovery in programming the self-assembly of molecules, enabling the creation of predictable and controllable structures with potential applications in various fields like sensing, drug delivery, and bioimaging.
Scientists from Trinity College Dublin have achieved a breakthrough in programming the self-assembly of molecules, leading to predictable and controllable outcomes. This discovery, published in the journal Nature Chemistry, holds immense potential for various applications, including highly sensitive sensors and targeted drug delivery systems. The ability of biological systems to self-assemble with precision has long fascinated scientists.
However, understanding and manipulating these processes has remained a significant challenge. This research team, led by Professor Thorfinnur Gunnlaugsson, has made significant strides by developing 'Malteser-like' molecules, composed of amino acids, that self-assemble into different structures depending on the specific amino acid sequence used. This precise control over self-assembly opens doors to numerous applications. For instance, these molecules could be used to create highly specific sensors for detecting various substances, or they could be employed in targeted drug delivery systems, where drugs are released only at the desired location in the body. This targeted approach could significantly reduce side effects associated with traditional therapies. Furthermore, the team discovered that incorporating lanthanide ions into these molecules enhances their luminescence, making them suitable for real-time monitoring of biological processes. This multidisciplinary collaboration between chemists, biochemists, materials scientists, and physicists highlights the power of collective expertise in pushing the boundaries of scientific discovery
Self-Assembly Molecular Programming Nanotechnology Sensors Drug Delivery Bioimaging Luminescence
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