Obesity is a predominant risk factor for cancer diagnosis — which means this weight loss drug hits two birds with one stone.
, published Tuesday in the journal Obesity, investigated the effects of obesity medications on the body’s “Natural Killer cells,” immune system cells that can attack tumor and virus cells. Obesity can disrupt the function of these immune cells, putting people with the condition at a higher risk of developing cancer.
The team analyzed a cohort of 20 patients with obesity, observing them for six months while using once-weekly injections of semaglutide, the drug in Wegovy and Ozempic. Their findings, which will be presented at the 30th European Congress on Obesity this month, suggest that the drug restored the function of the NK cells.
“My team and I are very excited by these new findings in relation to the effects of the GLP-1 treatment on people with obesity and it appears to result in real tangible benefits for those currently on the drug,” Dr. Andrew Hogan, the study’s principal investigator, said in aTypically prescribed to patients with type 2 diabetes, semaglutide — used in Ozempic and Wegovy — can also help people with obesity ward off cancer.
“We are finally reaching the point where medical treatments for the disease of obesity are being shown to prevent the complications of having obesity,” said professor Donal O’Shea, the national clinical lead for obesity with Ireland’s publicly funded healthcare system, the Health Service Executive. “The current findings represent very positive news for people living with obesity on GLP-1 therapy and suggest the benefits of this family of treatments may extend to a reduction in cancer risk.
But Hogan, who is also an associate professor at the university’s Kathleen Lonsdale Institute for Human Health, noted the drug’s worldwide shortage as a result of the “recent spike in popularity” of GLP-1 treatments due to
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