Scientists have created an intricate molecular map of the human body and its complex physiological processes based on the analysis of thousands of molecules in blood, urine and saliva samples from 391 volunteers.
The data was integrated to create a powerful, interactive visual web-based tool called Connecting Omics that can be used to investigate the complex molecular make-up of humans and discover underlying traits associated with various diseases.
"Our idea was to bring together everything we have learned over more than a decade of multiomics research to create a comprehensive molecular model of the human body and its processes," said senior author Dr. Karsten Suhre, professor of physiology and biophysics and a member of the Englander Institute of Precision Medicine.
The approach of combining genomic, transcriptomic, metabolomic, proteomic and other forms of so-called '-omics' research is known as 'multiomics.' This approach has emerged in recent years as a key strategy for biomedical researchers seeking to understand how the human body and diseases truly function, providing insights that could potentially enable the development of new drug therapies.
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