Kratom, used like an opioid, widely available online and elsewhere, and increasingly popular, can cause hyperpigmentation most commonly affecting sun-exposed areas of the face and hands.
CHICAGO —The use of kratom, an opioid-like supplement widely available over the counter at convenience stores, smoke shops, and online, is resulting in emerging cases of hyperpigmentation, most often on the face and hands.at the University of Miami Department of Dermatology, Miami, said at the Pigmentary Disorders Exchange Symposium.
Kratom also has many different effects on the psyche, Woolery-Lloyd said at the meeting. At low doses, it blocks the reuptake of norepinephrine, serotonin, and dopamine, producing a motivational effect, and at high doses, it creates an analgesic, calming effect. And people who chronically consume high doses of kratom may be susceptible to hyperpigmentation.
In the case report, Powell and coauthors described a 54-year-old White male patient who had been using kratom for the previous 4-5 years to reduce opioid use. During this period, he consumed kratom powder mixed with orange juice times a day. He presented with"diffuse hyperpigmented patches on his arms and face in a photodistributed manner, with notable sparing of the knuckles on both hands.
"The patient stopped using kratom in May 2022, but the discoloration remains. It has not regressed in the following 16 months after discontinuing kratom use," the authors wrote, noting that"whether or not the hyperpigmentation is able to regress is unknown.
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