First-generation antihistamines were associated with an increased risk for seizures in children aged 6-24 months.
First-generation antihistamines are linked to a 22% higher risk for seizures in children, new research shows. The risk appears to be most pronounced in children aged 6-24 months.Researchers in Korea used a self-controlled case-crossover design to assess the risk for seizures associated with prescriptions of first-generation antihistamines.
Prescriptions during the 15 days before a seizure were considered to have been received during a hazard period, whereas earlier prescriptions were considered to have been received during a control period.In an adjusted analysis, a prescription for an antihistamine during the hazard period was associated with a 22% higher risk for seizures in children .
Seizure Disorder Seizure Antihistamine Children Child Childhood Pediatrics Kids Febrile Seizure Fever Fit Febrile Convulsion Blood-Brain Barrier BBB - Blood Brain Barrier UK National Health Service United Kingdom National Health Service UK NHS NHS National Health Service
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