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Menthyl esters derived from menthol, such as MV and MI, have shown exceptional anti-inflammatory and potential anti-obesity effects in a new study. These compounds, tested in vitro and in animal models, surpass menthol’s capabilities, targeting specific receptors like the liver X receptor, and could offer new treatments for inflammatory and metabolic disorders.
Researchers developed menthyl esters with significant anti-inflammatory and anti-obesity effects, potentially offering new treatments for chronic inflammatory conditions and metabolic disorders. The menthyl esters of valine and isoleucine are multi-faceted molecules with enhanced anti-inflammatory and anti-obesity activities. The discovery and development of such molecules can result in newer classes of therapeutic drugs to treat a wide range of metabolic disorders. Credit: Gen-ichiro Arimura from Tokyo University of Science, Japan. Sharing the motivation behind the present work, Prof.
Menthyl esters possess unique advantages compared to other anti-inflammatory or anti-obesity compounds currently being researched or used. Their specific mechanisms of action, which contribute to their dual anti-inflammatory and anti-obesity effects sets them apart from other compounds and may make them particularly effective in addressing both inflammatory conditions and metabolic disorders.
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