New research shows that people with more fat stored within and around their muscles have a greater risk of heart disease complications, such as death or hospitalization. This association holds true regardless of BMI, suggesting that IMAT may be a valuable indicator of cardiovascular risk beyond traditional metrics.
Humans with relatively more fat hidden in and around their muscles face a higher risk of death or hospitalization from heart disease, according to new research – an association that persists regardless of body mass index .a potential risk factor for cardiovascular disease that warrants further study.
"Obesity is now one of the biggest global threats to cardiovascular health, yet body mass index – our main metric for defining obesity and thresholds for intervention – remains a controversial and flawed marker of cardiovascular prognosis," The study involved 669 subjects, all patients at Brigham and Women's Hospital with chest pain or shortness of breath but no signs of obstructive coronary artery disease. About 70 percent were women and 46 percent were non-white, with an average age of 63, the authors
Patients with elevated IMAT levels were more likely to have CMD, the study found, and faced a higher risk of death or hospitalization from heart disease.
HEART DISEASE FAT IN MUSCLE INTERMUSCULAR FAT BMI RISK FACTORS
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