Vicki McFarlane, a mother-of-one from Pickering, Yorkshire, has ditched Mounjaro, an appetite-suppressing jab, due to relentless nausea, unbearable headaches and 'eggy burps' she believes were caused by the jab. She has since lost weight after taking berberine, a supplement which costs her around 30p a day. This is a different process to weight-loss jabs like Mounjaro - officially named GLP-1 receptor agonists - which mimic a hormone the gut normally produces that helps control blood sugar and appetite after eating. Experts remain cautious about the use of berberine, highlighting that reviews of existing trials show 'modest results' and that the supplement may interfere with certain medications.
Vicki McFarlane, a mother-of-one from Pickering, Yorkshire, decided to stop using Mounjaro , an appetite-suppressing jab, due to relentless nausea, unbearable headaches and ' eggy burps ' she believes were caused by the jab.
Despite shedding two stone in as many months, she continued searching for alternative methods and came across an advert for berberine, a plant compound used in traditional Chinese medicine. Studies have shown some promise in modest weight loss when using berberine, but experts have urged caution. Ms McFarlane decided to order a pack of slow-release patches of berberine for £8.99, or around 30p a day.
The main benefit of berberine is thought to be that it triggers the release of AMP-activated protein kinase, an enzyme that lowers high blood sugar levels and instructs the cells to burn stored fat for energy. Ms McFarlane has since lost weight after taking berberine, a supplement which costs her around 30p a day.
This is a different process to weight-loss jabs like Mounjaro - officially named GLP-1 receptor agonists - which mimic a hormone the gut normally produces that helps control blood sugar and appetite after eating. The drug signals the pancreas to release insulin when blood sugar rises and slows how quickly food leaves the stomach, which helps people feel full sooner.
Ms McFarlane said she had been trying to lose another three or four stone forever - she was always on some diet or other. She lost weight on Mounjaro, but she felt so ill the whole time.
Then she read about berberine online - and she noticed the impact within a couple of days. Despite her initial scepticism, the results for Ms McFarlane have been impressive. From June to mid-October last year, she dropped from 17st 9lbs to 14st 2lbs - results she believes were as a result of no longer having a sweet tooth. Ms McFarlane says the results have also left her friends stunned, with many of them asking for the secret to her success.
Still, experts remain cautious. Duane Mellor, a dietitian and an honorary associate professor at the University of Leicester, highlighted that reviews of existing trials show 'modest results', including one in the Journal of Clinical Nutrition in 2022 which saw people lose 1-4kg (2-9lb) over eight to 12 weeks when taking 900-1,500mg of berberine per day.
He added that the supplement may interfere with the way the body processes certain medications, including blood thinners and statins, potentially increasing the risk of harmful side effects. For Ms McFarlane, one of berberine's biggest advantages is the absence of the side effects she experienced while taking Mounjaro, which cost her £180-a-month through an online provider
Vicki Mcfarlane Mounjaro Berberine Weight Loss Nausea Headaches Eggy Burps AMP-Activated Protein Kinase GLP-1 Receptor Agonists Duane Mellor University Of Leicester
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