Air Pollution Raises Risk of Deadly Kidney Disease

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Air Pollution Raises Risk of Deadly Kidney Disease
EnvironmentAir PollutionKidney Disease

A study in Sao Paulo, Brazil, found that poor air quality, linked to acute kidney injury and hospitalisation from kidney failure, significantly increases the threat of chronic kidney disease for people aged 19 to 50. Men were at higher risk than women.

Air pollution increases the risk of deadly kidney disease , research has revealed. The study found that poor air quality was also linked to acute kidney injury and hospitalisation from kidney failure.

The research in Sao Paulo, Brazil, between 2011 and 2021 analysed data from 37,000 people. It discovered that air pollution significantly increased the threat of chronic kidney disease for people aged 19 to 50. Those aged 51 to 75 were at up to 2.5 times increased risk. The researchers, at the University of Sao Paulo, also found that men were at higher risk than women of being hospitalised from the condition.

Their study found that exposure to high levels of pollution over 24 hours is sufficient to increase men's risk of hospitalisation for acute kidney injury. Air pollution increases the risk of deadly kidney disease, research has revealed That risk does not appear to rise in women – for reasons that are unclear, say the researchers.

'The hypothesis is that particulate matter can enter the bloodstream and deposit in kidney tissue, where it's recognised by the immune system as a foreign body, causing the body to produce a series of inflammatory mediators, as well as mediators of fibrosis and premature ageing,' says Professor Lucia Andrade, from the University of Sao Paulo Medical School which ran the study. Chronic kidney disease affects more than seven million Britons and contributes to around 45,000 deaths a year.

It often has no symptoms until kidneys are close to failing, leaving an estimated one million Britons unaware that they are ill. The average air pollution over the period of time in the study was three times World Health Organisation limits, a level that is rarely seen in the UK.

However, experts say that their findings demonstrate that there is a risk even at much lower levels of air pollution.

'Even concentrations within the limit showed a link to hospitalisations for kidney diseases, indicating the need to intensify policies to reduce air pollution,' says Dr Iara da Silva, lead author of the study.

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Environment Air Pollution Kidney Disease Research Sao Paulo Brazil Chronic Kidney Disease Acute Kidney Injury Hospitalization From Kidney Failure Exposure To High Levels Of Pollution Risk Of Chronic Kidney Disease Rarely Seen In The UK Need To Intensify Policies Link To Hospitalisations For Kidney Diseases

 

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