The propofol-ketamine combination significantly reduced the incidence of sedation-induced atelectasis and allowed faster emergence from anesthesia than propofol alone in children undergoing MRI.
Researchers at Samsung Medical Center in Seoul, Korea, compared the incidence of atelectasis after pediatric MRI sedation using a propofol-ketamine combination with that using propofol alone.
Overall, 107 children aged 3-12 years with American Society of Anesthesiologists physical status I-II who were undergoing elective 3T MRI under deep sedation were randomly assigned to receive either propofol or the propofol-ketamine combination. During MRI, patients in the propofol group received 0.2 mL/kg of 1% propofol and 2 mL of 0.9% saline, followed by a continuous infusion of propofol and 0.9% saline ; patients in the combination group received 0.2 mL/kg of 0.5% propofol and 1 mg/kg of ketamine, followed by a continuous infusion of propofol and ketamine .
The emergence time in the postanesthesia care unit was also shorter with the propofol-ketamine combination than with propofol alone encompassed a wide developmental spectrum, which may have affected the consistency of the findings. Baseline lung ultrasonography images were not obtained due to poor cooperation from conscious pediatric patients, limiting the ability to compare lung conditions before and after sedation.
This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.
Pain Management Procedural Sedation Children Child Childhood Pediatrics Kids Sedation In Children Pediatric Sedation Paediatric Sedation Sedation Sedative Sedative Use Atelectasis Pulmonary Atelectasis Lung Anesthesia Anesthetic Anesthaesia Anaesthetic Ultrasonography Ultrasound Sonogram Healthcare And Medical Technology Health And Medical Tech Health And Med Tech
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