The woman receiving the womb was born with Mayer-Rokitansky-Kuster-Hauser (MRKH), a rare condition that affects around one in every 5,000 women
A woman has been given a womb by her older sister in the UK’s first womb transplant. The 34-year-old married woman received the organ – also called the uterus – during an operation lasting nine hours and 20 minutes at the Churchill Hospital in Oxford, which is part of Oxford University Hospitals NHS Foundation Trust.
He added: “It was incredible. I think it was probably the most stressful week in my surgical career but also unbelievably positive. The donor and recipient are over the moon, just over the moon. I’m just really happy that we’ve got a donor who is completely back to normal after her big op and the recipient is, after her big op, doing really well on her immunosuppressive therapy and looking forward to hopefully having a baby.
. In MRKH, women have an underdeveloped vagina and underdeveloped or missing womb. The first sign of the condition is when a teenage girl does not have periods. Prof Smith said: “The operation surgically has been incredibly successful. The donor and the recipient are two absolutely lovely women. We couldn’t have a better result.
Asked if they felt nervous going into theatre, Prof Smith said: “Not nervous, I would say focused and well aware that failure was not an option.” The case was also reviewed by an HTA panel before permission was granted to proceed. The transplant cost of around £25,000 was paid for by donations to the Womb Transplant UK charity.
If the woman falls pregnant, she will be cared for in a specialist antenatal clinic at Queen Charlotte’s and Chelsea Hospital, where the delivery would also take place. To date, Womb Transplant UK has approval for 10 operations involving brain-dead donors plus five using a living donor, most likely a womb from a sister or mother. It currently has enough funds for four of these operations.
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