Cancer treatments can cause a wide variety of adverse side effects that require tailored diagnosis and treatment.
in Munich, Germany, specialists explored the manifestations of cutaneous drug reactions and how to manage them.In addition to chemotherapy, there are three other pillars of pharmacologic cancer therapy, as outlined by the first speaker, Mirjana Ziemer, MD, PhD, senior physician and dermatologist at University Hospital Leipzig, Leipzig, Germany:: Including B-Raf serine-threonine kinase, mitogen-activated protein kinase kinase, Hedgehog, and mammalian target of rapamycin inhibitors.
Ziemer noted that patients with lichenoid drug–induced rashes require comprehensive skin examinations, as these reactions can involve balanitis, vulvitis, and oral mucositis, often leading to treatment discontinuation.Although rare, severe exanthematous drug reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis are possible. Initial signs resemble erythema multiforme, which emerges rapidly after a new drug is administered.
. Systematic documentation of side effects helps to identify risk factors, pathogenesis, and effective treatments.Christoffer Gebhardt, MD, professor of dermatooncology at University Medical Center Hamburg-Eppendorf in Hamburg, Germany, highlighted side-effect management for two novel oncologic drugs. Tebentafusp, approved in 2022 for uveal melanoma, links T cells to the tumor antigen gp100 to facilitate tumor cell destruction, but it only works in patients who have the HLA-A*0201 genotype.
Skin Cancer Malignant Skin Neoplasm Adverse Effects Side Effects Biologic Therapy Biologics Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Tumor Melanoma Malignant Melanoma Targeted Therapy Targeted Cancer Therapy TNF-Alpha Tumor Necrosis Factor-Alpha TNF Alpha Cachexin Cachectin Genomics Genomic Medicine Toxicology Toxicity Poisoning Toxins
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Complications From Prostate Cancer Therapy Can Be Serious and Long-TermMen who undergo prostate cancer treatment face a greatly increased risk of life-altering, long-term complications, a new study finds.
Read more »
MIT’s new cancer therapy combines tumor destruction, chemo in single implantMIT scientists have developed implantable microparticles offering a dual-action cancer treatment, combining targeted phototherapy and chemotherapy.
Read more »
Charles’ Secret Trip to Indian Spa With Wacky Cancer TherapyThe king’s use of alternative therapies has helped him through his cancer journey, one friend told The Daily Beast.
Read more »
The Forgotten Developer of Tamoxifen, a Lifesaving Breast Cancer TherapyHer name was on the patent for tamoxifen, but Dora Richardson’s story was lost until now
Read more »
Overcoming Resistance to Checkpoint Inhibitor Cancer TherapyDr. William A. Haseltine is a distinguished scientist, philanthropist, author, and entrepreneur renowned for his pioneering work in genomics and regenerative medicine. A former Harvard Medical School professor, he has made many significant contributions to cancer and HIV/AIDS research.
Read more »
Protein degradation strategy offers new hope in cancer therapyA team of scientists has used a novel approach to identify protein degraders that target Pin1, a protein involved in pancreatic cancer development.
Read more »