Understanding the Differences Between High-Shear Mixing and High-Pressure Homogenization

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Understanding the Differences Between High-Shear Mixing and High-Pressure Homogenization
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Learn the key differences between two important methods of particle size reduction, homogenization and emulsification.

Sponsored by Genizer LLCReviewed by Aimee MolineuxNov 12 2024 High-shear mixing and high-pressure homogenization are two approaches to particle size reduction, homogenization, and emulsification. Each method is principally based on shear force but offers distinct advantages depending on application.Understanding Shear Force Shear force is any force corresponding to a material’s surface. In liquid, for example, this leads to friction between fluid particles, leading to particle size reduction.

High-pressure homogenization generates shear by propelling the sample through a thin tube. A Y-shaped diamond interaction chamber can be used to split a liquid sample in two before colliding the sample with itself. The narrow section before collision generates shear. Advantages and Disadvantages of High Shear Mixing and High-Pressure Homogenization High-shear mixing can accommodate more viscous samples and larger volumes than high-pressure homogenization, and it is generally more cost-effective. However, high-pressure homogenization has a narrower distribution and smaller particle size and is generally more precise.

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