Critics claim that drugs like semaglutide and other GLP-1s can dangerously sap away our muscle mass, but what does the current science actually tell us?
It’s hard to go a day without hearing something new about the latest diabetes and obesity medications, semaglutide and tirzepatide. Usually, the buzz is positive, but there has been a persistent claim made about these drugs that would make any potential user wary: They don’t only help you lose weight—they supposedly hollow out your muscle mass at the same time, making you weak and vulnerable to all sorts of future health problems down the line.
But that’s absolutely not what the research is showing. Compared to placebo, people on these drugs have reported a better quality of life and improved physical functioning. Some limited data have also suggested that these drugs can cause a loss of lean body mass but without actually compromising the quality of our muscles. “When I see my patients, they’ll say things like: ‘Well, I just feel so much better, I’m able to function so much better.
Medical Pharma GLP-1 Receptor Agonist Semaglutide Obesity Peptide Therapeutics GLP-1 Muscle Atrophy Anti-Obesity Medication Michael Weintraub Type 2 Diabetes Weight Loss Tirzepatide Glucagon-Like Peptide-1 Samuel Klein Diabetes Peptide Hormones Gizmodo
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