A recent meta-analysis in Nutrients examined recent studies on the cornelian cherry, Cornus mas L., for evidence of its cardiometabolic benefit.
By Dr. Liji Thomas, MDReviewed by Danielle Ellis, B.Sc.Jul 11 2024 The increasingly widespread use of herbal and other forms of alternative medicine has stimulated research into their purported effects on human health.
Raised liver enzymes are also markers, not of impaired liver function as in non-alcoholic fatty liver disease . as was long thought, but of developing type 2 diabetes mellitus . They are also associated with cardiovascular disease risk factors. Anthocyanins increase NO release from the endothelium, inhibit vasoconstrictor levels, and cause vasodilation.
Ursolic acid acts via multiple pathways to restore insulin sensitivity, improve glycogen levels, and stimulate glucose uptake by muscle cells, resolving the metabolic syndrome. Loganic acid also increases antioxidant activity with reduced formation of glycation and oxidation products. Three of the studies included people with metabolic-dysfunction-associated fatty liver disease . One included people with T2DM, one those with insulin resistance, and one comprised postmenopausal women.
Overall, there was a significant drop in body weight with a standardized mean difference of -0.27. The BMI also dropped with an SMD of -0.42. Despite this, waist circumference did not change after adjusting for inter-study heterogeneity.
Alanine Alternative Medicine Blood Blood Pressure Cardiovascular Disease Cholesterol Diabetes Diabetes Mellitus Dyslipidemia Fatty Liver Glucose Hba1c Insulin Insulin Resistance Lipoprotein Liver Liver Disease Medicine Metabolic Syndrome Nutrients Obesity Research Syndrome Triglyceride Type 2 Diabetes Weight Loss
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