Several socioeconomic and demographic factors, including older age and treatment location, affected the likelihood that patients with metastatic CRC received biomarker testing.
Several factors — most notably, older age, treatment in the community setting or at East South Central facilities, and a lower educational level in the area of residence — are associated with lower rates of microsatellite instability andData indicate that access to genetic testing and counseling for patients with CRC varies, but few studies have evaluated discrepancies across the United States.
Researchers analyzed data on disparate biomarker testing and its association with clinical outcomes on a national scale in 41,061 patients with metastatic CRC, diagnosed between 2010 and 2017. Data were obtained from the National Cancer Database, a hospital-based cancer registry in the United States, and the study was conducted between November 2022 and March 2024.testing, with sociodemographic factors such as age, race, ethnicity, educational level, median household income, insurance type, area of residence, facility type, and facility location evaluated.
In the population , 17.3% identified as Black, 78% as White, and 4.7% as other; 85% lived in a metropolitan setting, and 40.5% received treatment at a comprehensive community cancer program.
This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.
Metastatic CRC Mcrc Metastatic Colorectal Cancer (Mcrc) Colorectal Cancer Colorectal Cancer (CRC) Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Genomics Genomic Medicine Biomarker Biological Marker Multi-Biomarker Disease Activity MBDA Multibiomarker Disease Activity KRAS K-Ras V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homo Gtpase Kras
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