Startling New Research: Sickle Cell Disease Is 11 Times More Deadly Than Previously Thought

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Startling New Research: Sickle Cell Disease Is 11 Times More Deadly Than Previously Thought
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The hereditary illness affects 8 million individuals, disproportionately impacting young adults, adolescents, and children. A recent study indicates that the death toll attributed to sickle cell disease is likely 11 times higher than what mortality records alone suggest. Not only is the condition o

A new analysis shows that sickle cell disease is a leading cause of death across multiple age groups and is most prevalent in sub-Saharan Africa, where newborn screening and treatment access are urgently needed. Rising mortality rates since 2000 are primarily driven by population growth in South Asia and sub-Saharan Africa.

This implies that a healthcare provider treating a patient with sickle cell disease who passes away due to a stroke might be unaware that the individual had the condition, or may not recognize that sickle cell disease can cause stroke. As a result, the doctor may not list sickle cell disease as a cause of death for that individual.

In 2021, half a million babies were born with sickle cell disease, and more than three-quarters of these births were in sub-Saharan Africa. Under the analysis of total mortality burden , sickle cell disease was the 12th leading cause of death globally for children under the age of 5 years. However, total sickle cell disease mortality burden was among the top three causes of death in Portugal, Jamaica, Libya, Oman, and San Marino.

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