Stages I-III Screen-Detected CRC Boosts Disease-Free Survival Rates

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Stages I-III Screen-Detected CRC Boosts Disease-Free Survival Rates
Colorectal Cancer (CRC)Preventive ScreeningScreening
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Detection of CRC by screening led to a lower recurrence risk and better survival in patients with stages I-III disease than detection of CRC only after symptomatic presentation.

Patients with stages I-III screen-detected colorectal cancer have better disease-free survival rates than those with non-screen–detected CRC, an effect that was independent of patient, tumor, and treatment characteristics.Patients with screen-detected CRC have better stage-specific overall survival rates than those with non-screen–detected CRC, but the impact of screening on recurrence rates is unknown.

A retrospective study analyzed patients with CRC from the Netherlands Cancer Registry diagnosed by screening or not. Screen-detected CRC were identified in patients who underwent colonoscopy after a positive fecal immunochemical test , whereas non-screen–detected CRC were those that were detected in symptomatic patients.Researchers included 3725 patients with CRC , of which 1652 and 2073 patients had screen-detected and non-screen–detected CRC, respectively; CRC was distributed approximately evenly across stages I-III .

This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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