Researchers have unveiled the hidden intricacies of how sperm go from passive bystanders to dynamic swimmers. This transformation is a pivotal step in the journey to fertilization, and it hinges on the activation of a unique ion transporter.
Researchers at Stockholm University have unveiled the hidden intricacies of how sperm go from passive bystanders to dynamic swimmers. This transformation is a pivotal step in the journey to fertilization, and it hinges on the activation of a unique ion transporter.
"SLC9C1 operates like a highly sophisticated exchange system. It swaps protons from inside the cell for sodium ions from the outside, temporarily creating a less acidic environment within the sperm. This change in the internal environment triggers increased sperm motility," says David Drew, Professor in Biochemistry at Stockholm University.
"The VSD domain responds to the change in voltage by pushing its rodlike S4 helix inwards. This clears the way for ion exchange by SLC9C1, ultimately initiating sperm motility," says David Drew.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Sperm's secret voltage switch: Scientists unlock the mystery of motilityResearchers at Stockholm University have unveiled the hidden intricacies of how sperm go from passive bystanders to dynamic swimmers. This transformation is a pivotal step in the journey to fertilization, and it hinges on the activation of a unique ion transporter. Their research has been published in Nature.
Read more »
Scientists decode 'LEGO protein' that makes sperm swimStephanie Pappas is a contributing writer for Live Science, covering topics ranging from geoscience to archaeology to the human brain and behavior.
Read more »
Spectators to swimmers: Decoding sperm motility through voltage-switchInteresting Engineering is a cutting edge, leading community designed for all lovers of engineering, technology and science.
Read more »
Gene integral to initiating, sustaining sperm cell development identifiedWith male infertility a mounting global concern impacting approximately 12% of men, according to the National Institutes of Health, a Penn State research team has discovered a gene that plays a key role in initiating and sustaining spermatogenesis. The finding, they said, may open a door for future therapies to boost sperm counts.
Read more »
Transgender Netflix Writer Will Select Sperm Donor During Stage Show: ‘Witness Queer Family-Making’Source of breaking news and analysis, insightful commentary and original reporting, curated and written specifically for the new generation of independent and conservative thinkers.
Read more »
Transgender Netflix Writer to Seek Sperm Donor During Stage Show: ‘Witness Queer Family-Making’Source of breaking news and analysis, insightful commentary and original reporting, curated and written specifically for the new generation of independent and conservative thinkers.
Read more »