Spectators to swimmers: Decoding sperm motility through voltage-switch

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Spectators to swimmers: Decoding sperm motility through voltage-switch
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Now, the intricate details of how sperm transform from passive spectators to active swimmers have been revealed by researchers at Stockholm University. Activating a particular ion transporter is crucial for this transition, an important step on the road to fertilization.Medical research has revealed the composition of a sperm with DNA located at its head and its entry into the egg facilitated by the acrosome, which is located near the tip of a sperm's head.

According to the team, this protein is "exclusively found in sperm cells, and it is usually not active. However when the chemo-attractants interact with the sperm’s surface, everything changes," said aResearchers found that SLC9C1 operations are similar to a highly advanced exchange system. It briefly reduces the acidity of the environment inside theby exchanging protons from inside the cell for sodium ions from the outside.

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