Researchers urged treatment with radiation alone for women with local recurrences of endometrial cancer, after finding no benefit and higher toxicities with the addition of chemotherapy.
June 10, 2024For women with pelvic recurrences of grade 1 or 2 endometrial cancer , adding cisplatin to definitive radiation treatment may result in more acute toxicities and no clinical benefit. These patients can skip chemotherapy and receive radiation alone.
The researchers found no significant difference in progression-free survival between patients who received radiation alone and those who received chemoradiation. After a median follow-up of 62 months, median progression-free survival was not reached in the radiation alone group vs 73 months in the chemoradiation arm .
Endometrial Cancer Carcinoma Of The Endometrium Cancer Of The Endometrium Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Chemotherapy Toxicology Toxicity Poisoning Toxins Vaginal Bone Marrow Medulla Ossea Histology Of Bone Bone Histology Bones Histology Physician Assistants Radiation Therapy Radiotherapy Radiation Oncology Texas Travel Medicine Travel
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