Scientists use patterns of chemical changes in DNA to create 'age clocks' that estimate biological age, revealing how fast someone is aging.
The researchers found that CheekAge was closely linked to mortality in long-term data, outperforming earlier epigenetic clocks that were trained using blood sample data.Researchers in the United States have created a next-generation tool named CheekAge, which uses methylation patterns found in easily obtainable cheek cells.
Epigenetic markers are chemical changes to DNA that don’t alter the genetic code but can affect how genes work. Methylation is one such change, often linked to aging. Scientists use these patterns to create “age clocks” that estimate biological age, revealing how fast someone is aging. These participants were part of the University of Edinburgh’s Lothian Birth Cohorts program and had been monitored throughout their lives.
The researchers found that CheekAge was closely linked to mortality in long-term data, outperforming earlier epigenetic clocks that were trained using blood sample data.
Cheek Swab Epigenetic Markers Methylation
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