Popular weight loss drugs have been linked to gastrointestinal, mental health, and vision problems, but the benefits appear to outweigh the risks.
But they’re not without problems. In the early days of the social media craze, news reports often featured patients whose gastrointestinal side effects sent them to the emergency room .
Nausea was reported most frequently — 44.2% of semaglutide users dealt with it, compared with 40.2% for liraglutide and 31% for tirzepatide. Diarrhea, constipation, and vomiting also struck one quarter to one third of semaglutide patients, and slightly fewer for the other two medications.“We don’t know who’s going to do well and who’s not,” she said. “We start slowly, and usually things go OK.”
“Some people use food as something other than nutrition. They use food to soothe other psychological issues,” Apovian said. “When that’s taken away, the psychological issues are still there.” One drawback with all these studies is that they’re based on large databases rather than randomized controlled trials . When researchers focused on RCTs in a, they found a significant association with only one form of GLP-1, albiglutide — which was withdrawn from the market in 2017. The other six FDA-approved drugs didn’t show a statistically significant link.
Diabetes Mellitus Type Ii Type 2 Diabetes Type 2 DM T2DM T2D Obesity Obese Adverse Effects Side Effects Patient Safety Bariatric Surgery Obesity Surgery Weight Loss Surgery Weight Management Weight Loss Vision Care And Maintenance U.S. Food And Drug Administration United States Food And Drug Administration Fda Depression Abdominal Infection Pancreatitis
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