The new study sought to solve the mystery of how women’s bones remain unaffected even though they lose calcium to produce milk.
Researchers from the University of California at San Francisco and UC Davis discovered a hormone that keeps breastfeeding women’s bones strong, and it could help heal fractures, too.
After an “exhaustive search,” they finally identified CCN3, a hormone that behaved differently than others that neurons secrete. As per the press release, they were able to locate CCN3 in the same brain region in lactating female mice, but not the receptor, as of yet. In increasing the levels of CCN3 in female and male mice, their bone mass and strength improved in weeks, and dramatically. Remarkably, CCN3 doubled the amount of bone mass in very old female mice and those lacking estrogen.Dr. Thomas Ambrosi, a project collaborator, went on to say that highly mineralized bones aren’t always better as they can become weaker and break more easily. However, “when we tested these bones, they turned out to be much stronger than usual.
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