Researchers have figured out how to reduce hearing loss after exposure to loud noise: A drug for your gut called SPIOCA.
Exposure to loud noise is a risk factor for hearing loss. That's why it's great to see smart devices like the iPhone and AirPods notify you when the environmental sounds around you surpass a safe threshold. Also, wearing earphones like the AirPods when going to concerts can help reduce exposure to loud sounds. We can't prevent all the loud noises around us to reduce the risk of hearing loss after exposure.
was also created to survive the acidic conditions of the stomach on its way to the gut, where it's needed to act. They gave -treated subjects had better preservation of hair cells and, therefore, better hearing levels than the untreated ones. Loud sounds cause local inflammation. Reactive oxygen species accumulate in hair cells, damaging and potentially killing them. Without these tiny cells, we can't pick up sounds and experience hearing loss. The
drug managed to inhibit inrlammatory factors from the got from reaching the inner ear. Without the drug, the pro-inflammatory cytokines would increase and eventually reach the inner ear, where they might bypass the blood-labyrinth barrier that should protect the hearing organ from these cells. They would generate additional ROS, which threaten the integrity of hair cells.
doesn't just reduce these hair cells' exposure to inflammatory factors; it also improves the function of S1PR2 receptors in the ear and reduces damage. More research is needed before a
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