A team of researchers has developed an innovative computational tool that analyzes the gut microbiome, a complex ecosystem of trillions of bacteria, fungi, viruses and other microorganisms within the digestive system, to provide insights into overall well-being.
A team of Mayo Clinic researchers has developed an innovative computational tool that analyzes the gut microbiome, a complex ecosystem of trillions of bacteria, fungi, viruses and other microorganisms within the digestive system, to provide insights into overall well-being., the tool demonstrated at least 80% accuracy in differentiating healthy individuals from those with any disease.
The gut microbiome plays a crucial role in digestion, metabolism and immune function, and researchers are finding an imbalance in the gut microbiome can be linked to various chronic diseases. The tool development process involved identifying microbial species, carefully selecting the most relevant features and optimizing the machine learning model.
The team also tested its tool across various clinical scenarios, including people who had undergone fecal microbiota transplantation, as well as people who made changes in dietary fiber intake or who had antibiotic exposure, to demonstrate its ability to detect shifts in gut health.
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