Regeneron's antibody cocktail can reduce the risk of death in hospitalized Covid patients, a study finds. megtirrell has the details.
The British study — part of the wider Recovery trial investigating various possible treatments for people hospitalized with coronavirus — found that an antibody combination made byreduces the risk of death when given to patients with severe Covid who have not mounted a natural antibody response of their own.
But in a small trial in hospitalized patients, preliminary evidence suggested a clinical benefit for patients who had not mounted a natural antibody response of their own when they entered the trial. For patients who were seronegative at the start of the study, the antibody combination significantly reduced their chances of dying by one-fifth compared with those receiving usual care alone .
The treatment had no noticeable beneficial effect on patients who were seropositive at the start of the trial. "If they do not have antibodies then treatment with antibody-based drugs to the spike protein can reduce their risk of death and also time spent in hospital. Patients who have made their own antibodies to the virus do not benefit from the new treatment, which is important information given the cost of drugs."
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Regeneron Antibody Therapy Saves Lives Of Hospitalized Covid-19 Patients, Large U.K. Study FindsI am a London-based reporter for Forbes covering breaking news. Previously, I have worked as a reporter for a specialist legal publication covering big data and as a freelance journalist and policy analyst covering science, tech and health. I have a master’s degree in Biological Natural Sciences and a master’s degree in the History and Philosophy of Science from the University of Cambridge. Follow me on Twitter theroberthart or email me at rhartforbes.com
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