Until now, trials have not made a convincing case for the widespread use of expensive antibody therapies
AN ANTIBODY THERAPY from Regeneron, a firm in upstate New York, improves the survival of patients with covid-19 and offers renewed hope for the treatment of those most seriously ill with the disease. A study in British hospitals found that Regen-Cov saved the lives of many of those unable to make their own antibodies in response to SARS-CoV-2. Such “seronegative” individuals constituted about a third of the 9,785 hospital patients in the study.
Regen-Cov already has emergency authorisation for use in America, Brazil, Canada, the European Union and India, but remains an investigational drug in Britain and elsewhere. Even if authorisation follows in many other countries, though, access to it is likely to remain extremely restricted. Dr Swaminathan says more monoclonal-antibody factories need to be established around the world so that such treatments become accessible and affordable. Lack of availability of Regen-Cov will probably become a topic of interest to those who argue that intellectual property in covid-19-related technologies should be waived by the World Trade Organisation.
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