A look at the latest clinical approaches for early detection in this often-misdiagnosed patient population.
people in the United States, is a progressive neurodegenerative disorder marked by cognitive and behavioral impairment that significantly affects social and occupational functioning. AD typically occurs in patients over age 65 years, but research has uncovered a subtype of AD,in the United States, it poses unique diagnostic challenges.
, and progressive neuronal damage, there are several substantial key distinctions between the two types. Like LOAD, EOAD includes a wide range of symptoms, with memory loss being one of the most prominent. EOAD, however, often presents with atypical, which compared neuropsychological assessments of participants with EOAD or LOAD vs those of healthy controls, found that the EOAD group exhibited more pronounced deficits in visual perception, praxis, and executive tasks.
The extended time to diagnosis often results in substantial losses, including time and financial resources, which can be devastating for patients.associated with delayed diagnosis include treatment delays, anxiety related to prolonged uncertainty, and increased caregiver burden. Additionally, the psychological impact of an EOAD diagnosis is significant. Patients with EOAD have a higher likelihood ofcompared with patients with LOAD, according to a recent case study.
Patients with EOAD are frequently excluded from studies and clinical trials owing to their atypical symptoms and younger age. Theis a prospective longitudinal study following 400 participants with EOAD and 100 age-matched controls. The goals of LEADS are to define the clinical and biological characteristics of EOAD, develop specific biomarkers for future research, and establish a trial-ready network.
Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.Fast Five Quiz: Moderate-Stage Alzheimer's Disease
Alzheimer's Disease Alzheimer Disease Positron Emission Tomography PET PET Scan PET - Positron Emission Tomography Prognosis Quality Of Life QOL Health Related Quality Of Life Health-Related Quality Of Life HRQOL Mhealth Wireless Medicine Mobile Health Digital Medicine Future Of Medicine Diagnostics And Medical Device Diagnostics And Medical Devices
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