Patients who underwent nipple-sparing mastectomy had higher rates of positive margins and node involvement but were less likely to receive radiation therapy.
Nipple-sparing mastectomy has become increasingly popular for treating early-stage breast cancer given the cosmetic and functional benefits of the procedure. However, appropriate use of adjuvant radiation therapy following nipple-sparing mastectomy has not been characterized.
Researchers compared outcomes and appropriate uses of radiation therapy among 624,075 women diagnosed with cT1-3N0M0 invasive ductal or lobular breast cancer between 2004 and 2017 who underwent breast-conserving surgery or nipple-sparing mastectomy . The researchers compared the rates of postoperative radiation therapy for two standard indications — positive margins and pathologic node involvement — in patients who had breast-conserving surgery or nipple-sparing mastectomy.< .001) and, on multivariable analysis, a 15% higher risk for positive margins compared with those who had breast-conserving surgery and, on multivariable analysis, an 8% higher risk for node involvement . Overall, only 17.
This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.Key Takeaways in Early Breast Cancer From ASCO 2024
Malignant Breast Neoplasm Breast Carcinoma Aesthetic Medicine Facial Rejuvenation Breast Conserving Surgery Conservative Breast Surgery Breast Preservation Surgery Mastectomy Breast Surgery Radiation Therapy Radiotherapy Radiation Oncology Surgery Breast Mammary Gland Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm
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