Atrial fibrillation improved when linear ablation and ethanol infusion were added to pulmonary vein isolation in a randomized multicenter trial, but not all experts are convinced.
With the two add-ons to PVI,"freedom from AF recurrences without anti-arrhythmia drugs was achieved in 70.7% of patients, compared to 61.5% assigned to PVI alone," said Chenyang Jiang, MD, deputy director of the Cardiology Department at Sir Run Run Shaw Hospital at Zhejiang University in Hangzhou, China.
In the open-label PROMPT-AF trial, 498 patients from 12 participating hospitals in China were randomized to PVI alone or PVI plus linear ablation and ethanol infusion of the vein of Marshall. The primary endpoint was freedom from any atrial arrhythmias without the use of antiarrhythmic drugs for 12 months. Enrollment was open to patients with persistent AF, defined as lasting at least 3 months, that was refractory to at least one antiarrhythmic drug.
When the add-ons were combined with PVI, there was a 27% risk reduction in the primary endpoint at 12 months compared with PVI alone — favored the add-on group over the PVI-alone group numerically but not statistically. Ethanol infusion, which involves creating chemical lesions that affect both the epicardial and endocardial mitral isthmus, did show a benefit over catheter ablation alone in the=.04), but it provided the rationale for exploring how the combination of linear ablation and ethanol infusion could optimize the effect of PVI for persistent AF in the PROMPT-AF trial.
AF Afib A-Fib Afib Afib Atrial Fib Atrial Fibrillation (AF) Atrial Fibrillation (A-Fib) AF - Atrial Fibrillation Ablation Catheter Ablation Cardiac Ablation Veins Arrhythmia Heart Isolation Quarantine Hospitals Cardiovascular Imaging Cardiac Imaging CV Imaging Clinical Guidelines Guidelines Ejection Fraction EF - Ejection Fraction
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Wotancraft’s Armor Module Add-Ons Make Its Photo Bags Even BetterWotancraft's new rugged Armor Module series products expand the versatility of the company's photography bags.
Read more »
Sway Funded Introduces Add-Ons to Enhance Flexibility and Support for TradersCrypto Blog
Read more »
Alabama Football Celebrates Walk Ons During Victory Over Mercer: Roll Call, NovemberYour daily briefing on what's going on with Alabama athletics, including how to watch the Crimson Tide.
Read more »
EXCLUSIVE: Adore Me Wants to Take Bra and Panty Try-ons From Cringe to CoolAdore Me and Veesual take virtual try-ons from test to launch in just two months, and bra and panty shopping from cringey to futuristic cool.
Read more »
The 10 Best Sneakers, Slip-Ons, and Clogs for Nurses in 2024These are the best shoes for nurses, according to podiatrists and registered nurses. Shop our favorite picks from Crocs, Hoka, and other top brands.
Read more »
Sheriff's Office plans to add license plate readers in certain parts of San Diego CountyCity News Service is one of the largest regional news services in the country, serving the Southern California region.
Read more »