Polybrominated diphenyl ethers, or PBDEs, are fire-retardant chemicals that are found everywhere. A mouse study reports that probiotic supplementation can reduce the negative impacts of PBDEs on neurodevelopment, behavior, and metabolism.
Polybrominated diphenyl ethers, or PBDEs, are fire-retardant chemicals that are found everywhere -- upholstery, carpets, curtains, electronics, and even infant products. Known to disrupt hormones and persist in the environment, these pollutants have been detected in water, soil, air, food products, animals, human tissues, and even breast milk.reports that probiotic supplementation can reduce the negative impacts of PBDEs on neurodevelopment, behavior, and metabolism.
They found male offspring exposed to PBDEs had a delay in body weight gain. Further, their incisor eruption was abnormally timed. "Low birth weight, among other developmental markers, is an established predictor of adult health outcomes," he said."Sadly, underserved, low socioeconomic populations are disproportionately affected in terms of pollutant exposure and health outcomes."
According to Curras-Collazo, using gut microbiota-focused therapies before birth through the mother may help protect against developmental and adult diseases linked to toxic exposures. The research team found the PBDE mixture affected the gut microbiome in an age- and sex-dependent way. Maternal LR supplementation promoted the diversity of gut bacteria in female pups and prevented changes in these bacteria in male pups.
Curras-Collazo, Kozlova, and Denys were joined in the study by other UCR investigators: Rui Liu, Anthony E. Bishay, Elyza A. Do, Varadh Piamthai, Yash V. Korde, Crystal N. Luna, Artha A. Lam, and Dr. Ansel Hsiao.
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