Researchers looked for associations of plasma omega-3 and omega-6 polyunsaturated fatty acids with the incidence of cancer.
Higher plasma levels of omega-6 and omega-3 fatty acids are associated with a lower incidence of cancer. However, omega-3 fatty acids are linked to an increased risk for prostate cancer , specifically.Researchers looked for associations of plasma omega-3 and omega-6 polyunsaturated fatty acids with the incidence of cancer overall and 19 site-specific cancers in the large population-based prospective UK Biobank cohort.
They included 253,138 participants aged 37-73 years who were followed for an average of 12.9 years, with 29,838 diagnosed with cancer. Plasma levels of omega-3 and omega-6 fatty acids were measured using nuclear magnetic resonance and expressed as percentages of total fatty acids. Participants with cancer diagnoses at baseline, those who withdrew from the study, and those with missing data on plasma PUFAs were excluded.Higher plasma levels of omega-6 and omega-3 fatty acids were associated with a 2% and 1% reduction in overall cancer risk per SD increase, respectively (Omega-6 fatty acids were inversely associated with 14 site-specific cancers, whereas omega-3 fatty acids were inversely associated with five site-specific cancers.
This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.
Malignant Prostate Neoplasm Prostate Cancer Cancer Of The Prostate Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Genomics Genomic Medicine Cancer Risk Fatty Acids Plasma Georgia Prostatic
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