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In a new study, researchers have found that an Ozempic-style drug seems to slow the progression of Alzheimer's, adding to the growing list of potential
In the group who took the active drug liraglutide, a GLP-1 agonist predecessor to Ozempic and Wegovy's semaglutide, patients experienced cognitive decline 18 percent slower than those who took the placebo. As the organization's Dr. Maria Carillo enthused in both the press release and an These results, which are being presented this week at the Alzheimer's Association conference in Philadelphia, haven't yet been published in a peer-reviewed journal and very much need to be demonstrated by larger trials. This is especially true because the researchers who led the small trial didn't find, as they hoped, that liraglutide changes the rate at which the brain processes glucose.
"The slower loss of brain volume suggests liraglutide protects the brain, much like statins protect the heart," Edison explained. "While further research is needed, liraglutide may work through various mechanisms, such as reducing inflammation in the brain, lowering insulin resistance and the toxic effects of Alzheimer's biomarkers amyloid-beta and tau, and improving how the brain's nerve cells communicate.
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