In findings with potentially important implications for cervical cancer screening, scientists at the National Cancer Institute (NCI)-designated Montefiore Einstein Cancer Center (MECC) have developed a test for detecting a type of cervical cancer that Pap tests often miss.
Reviewed by Megan Craig, M.Sc.Sep 7 2023 The findings published online today in the Journal of the National Cancer Institute .
"Because ADCs are often missed by current screening methods, they have higher mortality rates than the more common cervical squamous cell cancer," Dr. Strickler added. "Our goal is to catch the disease early, before it develops into cancer." Dr. Strickler is also professor and head of the division of epidemiology and the Harold and Muriel Block Chair in Epidemiology and Population Health at Albert Einstein College of Medicine.
The MECC-developed HPV test assessed HPV 16, 18, and 45 in a novel way: by specifically looking at methylation levels. "The advent of next-generation genetic testing has opened up opportunities for us to more accurately detect oncogenic HPV strains and patterns in the genomes that correspond with the development of AIS and ADC," said Robert D. Burk, M.D.
"Our findings, if confirmed by clinical trials, suggest that women with a high methylation score may benefit from colposcopy and specialized tissue evaluation, beyond just a Pap test, which could lead to early diagnosis and treatment for ADC or the removal of AIS lesions before they develop into ADC," said Dr. Burk.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
New test shows promise for detecting hard-to-find cervical cancersIn findings with potentially important implications for cervical cancer screening, scientists at the Montefiore Einstein Cancer Center (MECC) have developed a test for detecting a type of cervical cancer that Pap tests often miss. The findings published online today in the JNCI: Journal of the National Cancer Institute.
Read more »
Royal Institute of British Architects' first black president begins roleThe Royal Institute of British Architects' first black president stresses the importance of diversity.
Read more »
Scan could guide use of drugs targeting a tumor's 'scaffold' to improve breast cancer treatmentResearchers have found a way to use a simple, non-invasive scan to tell whether an experimental approach to enhance treatment for breast cancer is effective. The new research, led by scientists at The Institute of Cancer Research, London, could help doctors visualize tumors and speed up the development of targeted therapies for breast cancer.
Read more »
Degree apprenticeships a 'no brainer' says instituteA student who has been working in marketing while doing a degree says she feels like she is 'winning'.
Read more »
- a game-changing novel antibiotic with no resistanceResearchers reported the discovery of a new antibiotic, clovibactin.
Read more »
Belfast author on being nominated for prestigious award for his debut novelMichael Magee's debut novel Close To Home narrowly missed out on the Waterstones debut novel of the year award
Read more »