Novel catalyst for green production of fine chemicals and pharmaceuticals

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Novel catalyst for green production of fine chemicals and pharmaceuticals
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Scientists have developed an innovative catalyst that achieves a significantly lower carbon footprint, paving the way for greener chemical and pharmaceutical manufacturing processes.

A team of researchers from the National University of Singapore led by Associate Professor Lu Jiong from the Department of Chemistry under the NUS Faculty of Science, together with their international collaborators, have developed a new class of catalysts -- known as heterogeneous geminal atom catalysts -- that promotes greener and more sustainable manufacturing processes for fine chemicals and pharmaceuticals.

The study was a collaboration involving Associate Professor Koh Ming Joo and Assistant Professor Zhu Ye from the Department of Chemistry under the NUS Faculty of Science, Professor Li Jun from Tsinghua University in China, Professor Javier Pérez-Ramírez from ETH Zurich in Switzerland and Dr Xi Shibo from the Agency for Science, Technology and Research in Singapore.The synthesis of organic compounds requires a series of steps known as transition metal-catalysed coupling reactions.

The research team then tested the newly developed catalyst in some chemical reactions involved in creating commonly used drugs and chemical compounds to demonstrate its efficiency compared to conventional catalysts, and researchers also quantified the environmental benefits of this new type of GACs.

The researchers also analysed the environmental benefits of using the novel catalyst in chemical reactions and found that it achieves a carbon footprint that is 10 times lower than using conventional catalysts.

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