New evidence supports the use of direct oral anticoagulants in the treatment of cerebral venous thrombosis.
Abu Dhabi, UAE — New evidence supports the use of direct oral anticoagulants in the treatment of cerebral venous thrombosis based on findings from a new prospective, observational study.
Patients are generally started on low-molecular weight heparin in the acute phase and then after several days switched to oral anticoagulation. Van de Munckhof said the DOAC-CVT trial was conducted to compare the safety and efficacy of DOACs vs vitamin K antagonists for the treatment of CVT in a setting that reflects the daily clinical practice.
The vast majority of study participants received heparin first, and the mean time to initiation of oral anticoagulation was 6 days in both groups. Symptomatic recurrent venous thrombosis occurred in 1.5% of the DOAC group vs 1.4% of the vitamin K antagonist group, and major bleeding occurred in 1.5% of the DOAC group and 1.8% of the vitamin K antagonist group.
Cerebrovascular Accident CVA - Cerebrovascular Accident Thromboembolism Cerebral Venous Thrombosis Cerebral Venous Sinus Thrombosis Venous Sinus Thrombosis Of The Brain Deep Venous Thrombosis DVT Deep Vein Thrombosis DVT - Deep Venous Thrombosis Thrombosis Vitamins Anticoagulation Therapy Anticoagulant Anticoagulation Traumatic Brain Injury TBI - Traumatic Brain Injury TBI
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