Month ? of quarantine.
For Marcus*, the shrooms trip that changed his life also turned him into a tree. There, in the middle of the woods, he melted into a"pattern of sacred geometry that looked like a Persian rug" — an experience that connected him to the rest of the forest, where he became one with every stick and even the ground."Everything was moving, breathing together in this connected way," Marcus recalls, a hint of awe evident in his voice.
Some of the most compelling results have come from the UK-based mental health company Compass Pathways' ongoing Phase III trials for a synthesized psilocybin drug that's been designated a"Breakthrough Therapy" for TRD by the FDA — which means the drug has proven so effective that the US government has fast-tracked its development and review so it can be publicly available sooner rather than later.
"But it's been an entirely politicized process," he continues."What that was was a resistance on the part of regulators to even look at the protocols, but for many researchers, there was so much stigma that they feared they would lose federal funding or be labeled a 'political radical,' so everything was stopped."
While these anecdotes may point to a correlation between microdosing and increased neuroplasticity, according to Burge, there is actually very little to no science-based research in terms of microdosing's efficacy itself, as compared to the aforementioned trials that have included much higher doses of psilocybin.
Whether we're talking chaga, lion's mane or shiitake, the explosive popularity of adaptogenic mushrooms — a subclass of adaptogens, i.e., plants, herbs or fungi that are supposedly able to help the body resist biochemical stressors of all kinds — have also begun to gain some serious traction, particularly amongst millennials.
Explaining that mushrooms in and of themselves contain complex carbohydrates called beta-glucans — which have immune-modulating and anti-tumor benefits — Joseph says that, in addition to strengthening the immune system, adaptogenic mushrooms can also help rebalance the body's reaction to stress.
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