In iron-deficient patients with heart failure and reduced or mildly reduced left ventricular ejection fraction, intravenous ferric carboxymaltose (FCM) is associated with a reduced risk of the composite outcome of total cardiovascular hospitalization and cardiovascular death through 52 weeks compared with placebo, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.
Iron deficiency is common in heart failure, with a prevalence of 30-80%, and is associated with increased mortality and hospitalization. Randomised controlled trials of intravenous iron in iron-deficient patients with heart failure have shown improvements in symptoms, functional capacity and quality of life, but the effect on clinical events has been unclear.
In the three trials, a total of 4,501 patients with heart failure and reduced or mildly reduced left ventricular ejection fraction and iron deficiency were randomly assigned to FCM or placebo . The mean age of the total population was 69 years, 63% were men, and the mean left ventricular ejection fraction was 32%.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Rain can't stop celebrations as thousands line streets for Manchester PrideFollowing a successful launch night in the Gay Village on Friday evening, today, all eyes were on the parade
Read more »
Weekend Hot Topic: The best level in a video gameReaders discuss their favourite level or open world area in a video game, from the opening of Bloodborne to the ending of Prince Of Persia.
Read more »
Creamfields set times and line up for final day on SundayThe final day of the festival will go out in style
Read more »
Three ways Man City could line up vs Sheffield Utd in the Premier LeagueManchester City travel to Bramall Lane to take on newly-promoted Sheffield United on Sunday, with Pep Guardiola absent after undergoing back surgery.
Read more »
Albon: Williams F1 straight-line reputation "not true" in ZandvoortWilliams Formula 1 driver Alex Albon says the team no longer has its traditional top speed advantage to exploit in Sunday's Dutch Grand Prix due to running more downforce.
Read more »
Neil Oliver leans into 'conspiracy' nickname with new line of T-shirtsTWO weeks into his boycott of Sainsbury’s for the crime of having security cameras at the tills, TV presenter-cum-conspiracy theorist Neil Oliver…
Read more »