Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs - Nature

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Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs - Nature
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A Nature research paper reports Phase II clinical results of PI3Kδ inhibition in solid tumors, and the exploration of immune adverse events

We thank C. Rommel, K. Ali, P. Johnson and D. Scott for support and help during the initial phases of setting up the CRUK/Amgen collaboration; F. Martin for project support over the years; M. Lopez and the research pathology core at University Hospital Southampton for performing the immunohistochemistry on the paraffin embedded material; I.

Lindsey Chudley, Joseph J. Sacco, Andrew Graeme Schache, Richard Shaw, Terry M. Jones, Pandurangan Vijayanand & Christian H. Ottensmeier Department of Otorhinolaryngology, Head and Neck Surgery, Ulm University Medical Center, Ulm, GermanyElena Lopez-Guadamillas & Bart VanhaesebroeckNicola A.

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