Injuries continue to deplete 49ers; McCaffrey, Mason both head to injured reserve

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Injuries continue to deplete 49ers; McCaffrey, Mason both head to injured reserve
San Francisco 49Ers
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The disastrous season for the San Francisco 49ers continued Monday with word of both the team's top running backs out for multiple weeks with five games left.

The disastrous season for the San Francisco 49ers continued Monday with word of both top running backs out for multiple weeks, the latest in a series of injuries as the team's playoff chances fizzle.

Rookie Isaac Guerendo, who ran for a 15-yard touchdown in the third quarter, now assumes the starting role for a depleted Niners team that has battled injuries to many of its starters all season. The 49ers were missing five starters against Buffalo. This season the team has lost Brandon Aiyuk, Jon Feliciano, Javon Hargrave, Talanoa Hufanga, and Elijah Mitchell to the injured reserve list.

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