Researchers have discovered that platelets secrete a protein that rejuvenates neurons in aged mice in a similar way to physical exercise. Pre-clinical trials have found that injecting this blood factor can replicate the benefits of exercise in the brain.
Researchers have found an injection of a specific blood factor can replicate the benefits of exercise in the brain. They've discovered that platelets secrete a protein, exerkine CXCL4/Platelet factor 4 or PF4, that rejuvenates neurons in aged mice in a similar way to physical exercise. This protein, which is released from platelets after exercise, results in regenerative and cognitive improvements when injected into aged mice.
Pre-clinical trials by University of Queensland researchers have found an injection of a specific blood factor can replicate the benefits of exercise in the brain. Dr Odette Leiter and Dr Tara Walker from UQ's Queensland Brain Institute led a team which discovered platelets, the tiny blood cells critical for blood clotting, secrete a protein that rejuvenates neurons in aged mice in a similar way to physical exercise. "We know exercise increases production of new neurons in the hippocampus, the part of the brain important for learning and memory, but the mechanism hasn't been clear," Dr Leiter sai
Injection Blood Factor Exercise Brain Platelets Protein Neurons Mice Regenerative Cognitive Improvements
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