Analysis of data from California prisons shows that both the number of COVID19 vaccine doses received and prior SARSCoV2 infection of index cases reduces the risk of virus transmission to close contacts nathanlo3579 UCSF
. We varied the start and the duration of the infectious period in sensitivity analyses. We shortened the assumed 5-day infectious period for a COVID-19 index case if the resident had a negative rapid antigen test during the infectious period. We excluded index cases if the resident had a negative PCR test during the infectious period to mitigate potential bias due to delayed detection of cases.
We defined a close contact of a COVID-19 index case as any resident who shared a cell with an index case while the index case was considered infectious, per the above definition. We further required a close contact to test negative for SARS-CoV-2 within 2 days before or after first exposure to an index case and to have follow-up testing within 3–14 days after last exposure. Close contacts were excluded if they had a prior SARS-CoV-2 infection in the preceding 90 days .
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