The randomized, controlled interventional trial also showed that circadian rhythm of the gut microbiome develops early and is detectable in vitro.
Diet has only a marginal impact on microbiome development in infancy, although metabolite profiles differ between breast- and formula-fed infants; circadian rhythm of the gut microbiome is detectable as early as 2 weeks after birth.
They also made note of the time of day that the stool sample was collected to assess 24-hour oscillations of the microbiome in relation to dietary exposure.Global microbiota assembly of infants is primarily affected by age and less so by diet. All infants showed a gradual increase in gut microbe diversity, and at 24 months, there was no observable difference between the groups.
GOS-supplemented formula was more effective at promoting sustained levels of bifidobacteria than formula containing bifidobacteria.
Microbiota Circadian Circadian Rhythm Diet Breast Mammary Gland Bacteria Bacterial Infection Birth Social Determinants Of Health SDOH Social Determinants Of Health (SDOH) Diversity Europe European Metabolism Metabolic Newborn Neonate Nutrition
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