Gepotidacin works by blocking enzymes that bacteria need to unzip their DNA -- their operating instructions -- so they can multiply in the body.
It was developed in partnership with the US government, as one of 19 projects currently funded by the Biomedical Advanced Research and Development Authority, or BARDA, to combat antimicrobial resistance. Government investment was needed because new drugs are expensive to develop, and antibiotics tend not to turn large profits.
"The antibiotic pipeline is what we would call pretty leaky, because, you know, you end up with antibiotics dropping out," Liu said, meaning many of the drugs don't make it from the first to second phase of human trials. Another round will drop out between the second and third phase, typically because companies run out of funds to develop them.
Urinary tract infections can happen to both men and women of any age, but are more common in women and girls, who have shorter urethras that are closer to the rectum, making it easier for bacteria to infect the urinary tract.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Neanderthal and Denisovan DNA Discovered in Ancient South AmericansTwo archaeological sites in Brazil are revealing the genetic ancestry of some of the continent’s earliest humans.
Read more »
Cold case DNA match was too late for attempted murder conviction, Ohio Supreme Court rulesThe Ohio Supreme Court ruled Ralph Bortree's conviction in a 1993 neck slashing case must be tossed out because the statute of limitations ran out.
Read more »
Traces Of Neanderthal, And Other Ancient Humans, May Still Live In Our DNA TodayGenetic research has uncovered ancient human lineages inside our own genomes, including Neanderthal and Denisovans DNA. And there’s likely still more to find.
Read more »
Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH - Nature GeneticsCRISPR-CATCH is used to isolate extrachromosomal DNA (ecDNA) molecules containing oncogenes from human cancer cells. CRISPR-CATCH followed by nanopore sequencing allows for methylation profiling, highlighting differences from the native chromosomal loci.
Read more »
How to get rid of UTI: FDA to consider new antibiotic for urinary tract infectionsGepotidacin works by blocking enzymes that bacteria need to unzip their DNA -- their operating instructions -- so they can multiply in the body.
Read more »