DYK: The lifetime cancer mortality rate for humans is about 20%. But for elephants, it's less than 5%. Research funded by theNCI and nlm_news studied how elephants avoid cancer–and how it could help prevent cancer in people: WorldElephantDay 🐘
Researchers may have discovered why elephants have a lower-than-expected rate of cancer.
Researchers have been trying to understand why some animals like elephants get cancer at rates much lower than expected.Cancer is caused by genetic changes, or DNA mutations, that allow cells to grow and divide uncontrollably. Researchers have extensively studied factors known to damage DNA, such as UV light and tobacco smoke, along with the cellular mechanisms of DNA repair.
A team led by Dr. Joshua Schiffman at the University of Utah set out to examine cancer rates in different species. They began by studying 14 years of autopsy data collected by the San Diego Zoo. They analyzed 36 species that spanned up to 6 orders of magnitude in size and life span—ranging from the 51-gram striped grass mouse, which lives a maximum of 4.5 years, to the elephant, which can live up to 65 years.
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