BEIJING (Reuters): A pill containing two HIV drugs that was touted as a potential treatment for the novel coronavirus was not effective, according to a study released late on Wednesday (March 18) in the New England Journal of Medicine.
A test in Chinese patients with severe Covid-19 disease found the 99 who received AbbVie Inc's Kaletra, a combination of lopinavir and ritonavir, fared no better than the 100 who received standard care.
People on the drugs showed clinical improvement after a median of 15 days compared to 16 days with standard care, a difference the researchers characterised as"significant, albeit modest".The lopinavir-ritonavir combination also produced more side effects, prompting the treatments to be halted in 13.8 per cent of patients.
All of the patients had pneumonia and were treated at Jin Yin-Tan Hospital in Wuhan, the city where the pandemic began.
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